Leptin: If It Does Not Work in Obese Humans, What Is Its Role in Energy Regulation? explores the involvement of leptin in energy regulation. Initially, the DVD looks at the traditional viewpoint of leptin providing negative adiposity-related feedback in a homeostatic model of energy regulation, and then details the various limitations of such a perspective. The DVD also offers a new point of view regarding the actions of leptin-that it serves as a mediator of sympathetic restraint with regard to the upper limit of an individual's body mass.
Among the topics covered:
• Leptin as adipostatic negative feedback
• Discrepancies in the homeostatic model
• New perspective on leptin actions
• High plasma leptin actions
Among the topics covered:
• Leptin as adipostatic negative feedback
• Discrepancies in the homeostatic model
• New perspective on leptin actions
• High plasma leptin actions