AMSSM Founders’ Keynote Talks: Past, Present, and Future of Sports Medicine features four of the original founders of AMSSM, sharing their information, ideas, and insights concerning AMSSM. In the first session, the origins of AMSSM are reviewed—the who, why, how, and when. The next presentation discusses the fact that knowledge and education are the recurrent threads of AMSSM. Next, the video looks at the evolution of sports medicine-related research over the course of the first 25 years of AMSSM’s existence. Finally, the video hypothesizes on the future of AMSSM, detailing six major forces that likely will shape the future.